Differential transcriptional regulation of the NANOG gene in chicken primordial germ cells and embryonic stem cells.

Hee Jung ChoiSo Dam JinDeivendran RengarajJin Hwa KimBertrand PainJae-Yong Han

Published in: Journal of animal science and biotechnology (2021)

We show for the first time that different trans-regulatory elements control transcription of cNANOG in a cell type-specific manner. This finding might help to elucidate the mechanism that regulates cNANOG expression in PGCs and ESCs.

Keyphrases

embryonic stem cells
induced apoptosis
transcription factor
poor prognosis
cell cycle arrest
copy number
endoplasmic reticulum stress
signaling pathway
binding protein
oxidative stress
cell death
dna methylation
gene expression
genome wide identification
pi k akt