High TNFRSF12A level associated with MMP-9 overexpression is linked to poor prognosis in breast cancer: Gene set enrichment analysis and validation in large-scale cohorts.

Jungho YangKyueng Whan MinDong-Hoon KimByoung Kwan SonKyoung Min MoonYoung Chan WiSeong Sik BangYoung Ha OhSung-Im DoSeoung Wan ChaeSukjoong OhYoung Hwan KimMi Jung Kwon

Published in: PloS one (2018)

High levels of TNFRSF12A associated with MMP-9 overexpression may be important to explain the progression of breast cancer, and survival could be improved using therapy targeting TNFRSF12A.

Keyphrases

poor prognosis
long non coding rna
cell proliferation
transcription factor
cell migration
copy number
genome wide
stem cells
young adults
genome wide identification
breast cancer risk
smoking cessation