MiR-137-3p Inhibits Colorectal Cancer Cell Migration by Regulating a KDM1A-Dependent Epithelial-Mesenchymal Transition.

Xiaoling DingJie ZhangZiqin FengQianru TangXiaorong Zhou

Published in: Digestive diseases and sciences (2020)

We conclude that MiR-137-3p inhibits CRC cell migration by regulating a KDM1A-dependent EMT process. Our study suggests that restoring the expression of miR-137-3p or targeting KDM1A might be potential therapeutic strategies for CRC.

Keyphrases

cell migration
epithelial mesenchymal transition
poor prognosis
transforming growth factor
signaling pathway
cancer therapy
risk assessment
drug delivery
human health