Effects of Polyphenol-Rich Interventions on Cognition and Brain Health in Healthy Young and Middle-Aged Adults: Systematic Review and Meta-Analysis.
Achraf AmmarKhaled TrabelsiOmar BoukhrisBassem BouazizPatrick MüllerJordan M GlennNicholas T BottNotger MüllerHamdi ChtourouTarak DrissAnita HökelmannPublished in: Journal of clinical medicine (2020)
This meta-analysis provides promising findings regarding the usefulness of polyphenol-rich intervention as an inexpensive approach for enhancing circulation of pro-cognitive neurotrophic factors. These beneficial effects appear to depend on the supplementation protocols. An early acute and/or chronic application of low- to high-dose phenolic components with high bioavailability rates (≥30%) at a younger age appear to provide more promising effects.
Keyphrases
- middle aged
- high dose
- systematic review
- white matter
- randomized controlled trial
- liver failure
- public health
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- low dose
- drug induced
- meta analyses
- mental health
- physical activity
- resting state
- aortic dissection
- health information
- multiple sclerosis
- health promotion
- cerebral ischemia
- intensive care unit
- climate change
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