Associations among environmental exposure to trace elements and biomarkers of early kidney damage in the pediatric population.
Manolo Ortega-RomeroElodia Rojas-LimaJuan Carlos Rubio-GutiérrezOctavio Gamaliel Aztatzi-AguilarJuana Narváez-MoralesMariela Esparza-GarcíaÁngel Barrera-HernándezMiguel Ángel MejiaPablo Mendez-HernándezMara MedeirosOlivier Christophe BarbierPublished in: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine (2024)
and Conclusions. Among the explored metals, exposure to Cu and iodine impairs renal function. In contrast, Se may manifest as a beneficial metal. Interactions of Mo-Se and Mo-Iodine seem to alter the expression of NGAL; Mo-Cu for CLU; Mo-Cu, Mo-Se, and Mo-iodine for Cys-C and a-1MG; and Mo-Cu and Mo-iodine for KIM-1; were noticed. Our study could suggest that trace element interactions were associated with early kidney damage biomarkers.