Caveolin-1 expression predicts favourable outcome and correlates with PDGFRA mutations in gastrointestinal stromal tumours (GISTs).

Luca Bertero Alessandro GambellaAntonella BarrecaSimona Osella-AbateLuigi ChiusaPaola Francia di CellePatrizia ListaMauro PapottiPaola Cassoni

Published in: Journal of clinical pathology (2021)

Caveolin-1 represents a novel prognostic marker in gastrointestinal stromal tumours. Further studies are warranted to validate these results and to explore the mechanisms linking Caveolin-1 expression with the PDGFRA oncogenic pathway.

Keyphrases

poor prognosis
binding protein
long non coding rna
transcription factor
case control