Association between vitamin D supplementation or serum vitamin D level and susceptibility to SARS-CoV-2 infection or COVID-19 including clinical course, morbidity and mortality outcomes? A systematic review.
Amy Louise GroveOsemeke OsokoguLena Al-KhudairyAmin MehrabianMandana ZanganehAnna BrownRachel CourtSian Taylor-PhillipsOlalekan Abdulrahman UthmanNoel McCarthySudhesh KumarAileen ClarkePublished in: BMJ open (2021)
There is no robust evidence of a negative association between vitamin D and COVID-19. No relevant randomised controlled trials were identified and there is no robust peer-reviewed published evidence of association between vitamin D levels and severity of symptoms or mortality due to COVID-19. Guideline producers should acknowledge that benefits of vitamin D supplementation in COVID-19 are as yet unproven despite increasing interest.