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Association between vitamin D supplementation or serum vitamin D level and susceptibility to SARS-CoV-2 infection or COVID-19 including clinical course, morbidity and mortality outcomes? A systematic review.

Amy Louise GroveOsemeke OsokoguLena Al-KhudairyAmin MehrabianMandana ZanganehAnna BrownRachel CourtSian Taylor-PhillipsOlalekan Abdulrahman UthmanNoel McCarthySudhesh KumarAileen Clarke
Published in: BMJ open (2021)
There is no robust evidence of a negative association between vitamin D and COVID-19. No relevant randomised controlled trials were identified and there is no robust peer-reviewed published evidence of association between vitamin D levels and severity of symptoms or mortality due to COVID-19. Guideline producers should acknowledge that benefits of vitamin D supplementation in COVID-19 are as yet unproven despite increasing interest.
Keyphrases
  • coronavirus disease
  • sars cov
  • respiratory syndrome coronavirus
  • randomized controlled trial
  • systematic review
  • metabolic syndrome
  • risk factors
  • adipose tissue
  • coronary artery disease