The natural sequence in which subclinically inflamed joint tissues subside or progress to rheumatoid arthritis: a study on serial MRIs in the TREAT EARLIER trial.
Doortje Isabelle KrijbolderXanthe Marijn Edmée MatthijssenBastiaan T van DijkHanna W van SteenbergenDebbie M BoetersAnnemiek WillemzeAnne A SchouffoerAnnette H M van der Helm-van MilPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2023)
Natural sequences in subclinical inflammation of different joint tissues were identified, deepening our understanding of clinical arthritis and RA-development. During progression to RA, increasing osteitis followed previous increases in tenosynovitis/synovitis. During pain-resolution, tenosynovitis decreased first, followed by decreasing synovitis and osteitis. This article is protected by copyright. All rights reserved.