Comparing the efficacy and tolerability of biologic therapies in psoriasis: an updated network meta-analysis.
S K MahilMartinsixtus C EzejimoforLesley S ExtonLina ManounahA D BurdenLaura C CoatesM de BritoA McGuireR MurphyC M OwenR ParslewRichard T WoolfZenas Zee Ngai YiuO A UthmanM Firouz Mohd MustapaCatherine H SmithPublished in: The British journal of dermatology (2020)
Using our methodology we found that most biologics cluster together with respect to short-term efficacy and tolerability, and we did not identify any single agent as 'best'. These data need to be interpreted in the context of longer-term efficacy, effectiveness data, safety, posology and drug acquisition costs when making treatment decisions.