Identification of CD64 as a marker for the destructive potential of synovitis in osteoarthritis.

Iris J Teunissen van ManenNienke J T van KootenIrene Di CeglieWessel F TheeuwesPilar Jimenez-RoyoMatthew ClevelandPeter L E M van LentPeter M van der KraanArjen B BlomMartijn H J van den Bosch

Published in: Rheumatology (Oxford, England) (2023)

Together, these results indicate that synovial CD64 expression is associated with the expression of proteolytic enzymes and inflammatory markers related to structural damage in OA. CD64 therefore holds promise as marker to characterize the damaging potential of synovitis.

Keyphrases

poor prognosis
nk cells
knee osteoarthritis
rheumatoid arthritis
oxidative stress
long non coding rna
machine learning
risk assessment
human health