The endothelial function biomarker soluble E-selectin is associated with nonalcoholic fatty liver disease.
Nynke SimonsMitchell BijnenKristiaan A M WoutersSander S RensenJoline Wilhelma Johanna BeulensMarleen M J van GreevenbroekLeendert M 't HartJan Willem M GreveCarla J H van der KallenNicolaas C SchaperMiranda T SchramCoen D A StehouwerMartijn C G J BrouwersPublished in: Liver international : official journal of the International Association for the Study of the Liver (2020)
NAFLD and related markers are associated with higher expression of hepatic E-selectin and higher levels of plasma sE-selectin. Further studies are required to investigate the role of E-selectin in the pathogenesis of NAFLD and the applicability of sE-selectin as a plasma biomarker of NAFLD/NASH.
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