Potential of Hibiscus sabdariffa Linn. in managing FGF21 resistance in diet-induced-obesity rats via miR-34a regulation.

Neng Tine KartinahNisa KomaraNuraini Diah NoviatiSyarifah DewiSophie YolandaAfifa RadhinaHeriyanto HeriyantoImelda Rosalyn Sianipar

Published in: Veterinary medicine and science (2021)

H. sabdariffa has the potential to reduce FGF21 resistance in DIO rats through the suppression of miR-34a expression and an increase in the number of FGFR1 and beta-klotho receptors in adipose tissue.

Keyphrases

long non coding rna
cell proliferation
adipose tissue
poor prognosis
insulin resistance
long noncoding rna
metabolic syndrome
type diabetes
weight gain
binding protein
skeletal muscle