Histological pattern and gene expression profiling of thyroid tissue in subjects with obesity.
Alessio BasoloA M PomaR GianniniG CeccariniC PelosiniP FierabracciM U CastanyS Bechi GenzanoC E AmbrosiniG MaterazziL ChiovatoF BasoloF SantiniL TorregrossaPublished in: Journal of endocrinological investigation (2021)
Increased BMI is associated with adipocyte and lymphocyte infiltration of the thyroid, not related to an autoimmune process, which might affect thyroid function in subjects with obesity. A differential gene expression profiling of metabolic and immune pathways in thyroid tissues of patients with obesity was also observed.