Decreased Expression of Sam68 Is Associated with Insulin Resistance in Granulosa Cells from PCOS Patients.
Teresa Vilariño-GarcíaPilar GuadixMónica Dorado-SilvaPascual Sánchez-MartínAntonio Pérez-PérezVíctor Sánchez-MargaletPublished in: Cells (2022)
These results suggest the participation of Sam68 in insulin receptor signaling, mediating the insulin effect in granulosa cells, and they suggest the possible role of Sam68 in the insulin resistance of PCOS.
Keyphrases
- polycystic ovary syndrome
- insulin resistance
- type diabetes
- end stage renal disease
- chronic kidney disease
- induced apoptosis
- ejection fraction
- newly diagnosed
- glycemic control
- poor prognosis
- prognostic factors
- adipose tissue
- physical activity
- peritoneal dialysis
- high fat diet
- patient reported outcomes
- long non coding rna