Adipose Tissue Analysis Toolkit (ATAT) for automated analysis of adipocyte size and extracellular matrix in white adipose tissue.

Jacob J RobinoAlexander P PlekhanovQingzhang ZhuMichael D Jensen Jan-Bernd FunckeCharles T RobertsOleg Varlamov

Published in: Obesity (Silver Spring, Md.) (2024)

ATAT provides several advantages over existing WAT image analysis tools, enabling high-throughput analyses of adipocyte-specific parameters and facilitating the assessment of ECM changes associated with WAT remodeling due to weight changes and other pathophysiological alterations that affect WAT function.

Keyphrases

adipose tissue
extracellular matrix
high throughput
insulin resistance
high fat diet
machine learning
physical activity
single cell
body mass index
weight loss
deep learning
fatty acid
weight gain
metabolic syndrome
type diabetes
body weight
skeletal muscle
data analysis
clinical evaluation