Low ZCCHC9 Gene Expression in Peripheral Blood May Be an Acute Myocardial Infarction Genetic Molecular Marker in Patients with Stable Coronary Atherosclerotic Disease.
Lihong LiHeyu MengXue WangJianjun RuanXiaomin TianFanbo MengPublished in: International journal of general medicine (2022)
ZCCHC9 gene expression in peripheral blood was significantly lower in patients with AMI than in stable CAD patients. Individuals with low expression of ZCCHC9 in peripheral blood have higher a probability to develop AMI than those with stable CAD. Thus, lowered ZCCHC9 gene expression can act as an independent risk factor for AMI.
Keyphrases
- peripheral blood
- gene expression
- acute myocardial infarction
- coronary artery disease
- percutaneous coronary intervention
- dna methylation
- end stage renal disease
- left ventricular
- ejection fraction
- newly diagnosed
- chronic kidney disease
- poor prognosis
- peritoneal dialysis
- coronary artery
- prognostic factors
- heart failure
- aortic stenosis
- patient reported
- patient reported outcomes
- long non coding rna