Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells.

Jin SeokHyun Sook JungSohae ParkJung Ok LeeChong Jai KimGi Jin Kim

Published in: Stem cell research & therapy (2020)

These findings suggest that alteration of FAO by increased CPT1A plays an important role in mitochondrial dysfunction and senescence of PD-MSCs during long-term cultivation.

Keyphrases

fatty acid
dna damage
endothelial cells
stress induced
mesenchymal stem cells
hydrogen peroxide