Asiatic Acid Interferes with Invasion and Proliferation of Breast Cancer Cells by Inhibiting WAVE3 Activation through PI3K/AKT Signaling Pathway.

Xiao-Jun GouHuan-Huan BaiLi-Wei LiuHong-Yu ChenFenggang HouLi-Sheng ChangMing-Ming DingQin ShiMei-Xiang ZhouWen-Li Chen Li-Min Zhang

Published in: BioMed research international (2020)

Asiatic acid interferes with the ability of breast cancer cells to invade and proliferate by inhibiting WAVE3 expression and activation and the mechanism of action may be related to the PI3K/AKT signaling pathway.

Keyphrases

signaling pathway
pi k akt
breast cancer cells
induced apoptosis
epithelial mesenchymal transition
cell cycle arrest
poor prognosis
cell migration