Expression of MAGE A1 to MAGE A10 in the Forceps Biopsy and Bronchoalveolar Lavage Specimens from Patients with the Central Lung Tumor.
Gondo MastutikAlphania RahniayuIsnin Anang MarhanaMochamad AminSiti Eriaty Nur RuslanHeru Fajar TriantoPublished in: Asian Pacific journal of cancer prevention : APJCP (2024)
The MAGE A subtype family genes are highly expressed in central lung tumor patients from FB and BAL specimens, even in specimens that were diagnosed with no malignant cells. All BAL specimens were diagnosed as no malignant cells, but expression of the MAGE A subfamily genes was found in more than 80% of the specimens. These observations suggest that combining histopathological and molecular examination could improve the diagnosis of lung malignancy.
Keyphrases
- fine needle aspiration
- induced apoptosis
- poor prognosis
- cell cycle arrest
- end stage renal disease
- ultrasound guided
- genome wide
- newly diagnosed
- ejection fraction
- genome wide identification
- chronic kidney disease
- prognostic factors
- binding protein
- gene expression
- cell proliferation
- signaling pathway
- dna methylation
- transcription factor