Regulation of Ferroptosis by non-coding RNAs: Mechanistic insights .
Ammad Ahmad FarooqıGulnara KapanovaSundetgali KalmakhanovAbay Z KussainovZaure DatkhayevaPublished in: The Journal of pharmacology and experimental therapeutics (2022)
Discovery of ferroptosis has paradigmatically shifted our understanding about different types of cell death. Wealth of information gathered over decades of pioneering research has enabled us to develop a better comprehension about versatile regulators of ferroptosis. In this review we have attempted to set spotlight on the indispensable involvement of non-coding RNAs in regulation of ferroptosis. We have exclusively analyzed role of miRNAs, long non-coding RNAs (lncRNAs) and circular RNAs in the regulation of ferroptosis and how inhibition of ferroptosis promoted carcinogenesis and metastasis. Significance Statement The review is written by experts in the field to bring our most recent information about this exciting topic.