Bisphenol A enhances adipogenic signaling pathways in human mesenchymal stem cells.
Amin SalehpourShidfar FarzadMehdi HedayatiAsal Neshatbini TehraniAli Asghar FarshadSaeed MohammadiPublished in: Genes and environment : the official journal of the Japanese Environmental Mutagen Society (2020)
Our findings supported the hypothesis that BPA enhances adipogenic differentiation thereby may play a role in development of obesity and dysregulation of metabolic homoeostasis.
Keyphrases
- mesenchymal stem cells
- endothelial cells
- signaling pathway
- metabolic syndrome
- insulin resistance
- weight loss
- type diabetes
- umbilical cord
- induced pluripotent stem cells
- weight gain
- pluripotent stem cells
- high fat diet induced
- pi k akt
- bone marrow
- stem cells
- adipose tissue
- epithelial mesenchymal transition
- oxidative stress
- skeletal muscle
- physical activity
- induced apoptosis