Micellar Curcumin: Pharmacokinetics and Effects on Inflammation Markers and PCSK-9 Concentrations in Healthy Subjects in a Double-Blind, Randomized, Active-Controlled, Crossover Trial.

Juergen GrafenederUlla DerhaschnigFarsad EskandaryNina BuchteleNadine SusJan FrankBernd JilmaChristian Schoergenhofer

Published in: Molecular nutrition & food research (2022)

Micellar curcumin demonstrates an improved oral bioavailability but does not show anti-inflammatory effects in this model. Potential effects on PCSK9 concentrations warrant further investigation.

Keyphrases

phase iii
open label
double blind
placebo controlled
phase ii
clinical trial
study protocol
oxidative stress
low density lipoprotein
randomized controlled trial
human health
risk assessment
climate change