Pharmacokinetics of Direct Oral Anticoagulants in Emergency Situations: Results of the Prospective Observational RADOA-Registry.
Edelgard Lindhoff-LastIngvild BirschmannJoachim KuhnSimone LindauStavros V KonstantinidesOliver GrottkeUlrike Nowak-GöttlJessica LucksBarbara ZydekChristian von HeymannAriane SümnigJan Beyer-WestendorfSebastian SchellongPatrick MeybohmAndreas GreinacherEva Herrmannnull nullPublished in: Thrombosis and haemostasis (2021)
Emergency patients under DOAC treatment show a high variation of anticoagulant concentrations at baseline. Compared with rivaroxaban, apixaban showed a lower median concentration on admission and a longer t ½.