Capturing Exacerbations of Chronic Obstructive Pulmonary Disease with EXACT. A Subanalysis of FLAME.
Stefan-Marian FrentKenneth R ChapmanMichael LarbigAlexander MackayRobert FogelFlorian S GutzwillerSteven ShenFrancesco PatalanoDonald BanerjiKonstantinos KostikasJadwiga A WedzichaPublished in: American journal of respiratory and critical care medicine (2019)
Regardless of the exacerbation definition used, our findings support the use of long-acting β2 agonists/long-acting muscarinic receptor antagonists as the preferred treatment option for patients at risk of future exacerbations. Clinical trial registered with www.clinicaltrials.gov (NCT01782326).