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The Cross-sectional and Longitudinal Association Between Thyroid Function and Depression: A Population-Based Study.

Oscar Hernando Roa DueñasAmy HofmanAnnemarie I LuikMarco MediciRobin P PeetersLayal Chaker
Published in: The Journal of clinical endocrinology and metabolism (2023)
We show a cross-sectional association between thyroid (dys-)function with depressive symptoms, and a U-shaped association between FT4 and incident depressive events in euthyroid individuals. Our findings suggest an association of thyroid function with the risk of developing depression, albeit small. Reverse causation and additional underlying factors may also contribute to the association.
Keyphrases
  • depressive symptoms
  • cross sectional
  • sleep quality
  • cardiovascular disease
  • stress induced