The Cross-sectional and Longitudinal Association Between Thyroid Function and Depression: A Population-Based Study.

Oscar Hernando Roa DueñasAmy HofmanAnnemarie I LuikMarco Medici Robin P PeetersLayal Chaker

Published in: The Journal of clinical endocrinology and metabolism (2023)

We show a cross-sectional association between thyroid (dys-)function with depressive symptoms, and a U-shaped association between FT4 and incident depressive events in euthyroid individuals. Our findings suggest an association of thyroid function with the risk of developing depression, albeit small. Reverse causation and additional underlying factors may also contribute to the association.

Keyphrases

depressive symptoms
cross sectional
sleep quality
cardiovascular disease
stress induced