Risk factors associated with the development of double-inlet ventricle congenital heart disease.
Sharon L PaigeWei YangJames R PriestLorenzo D BottoGary M ShawRonnie Thomad Collinsnull nullPublished in: Birth defects research (2019)
Maternal pre-pregnancy diabetes and history of insulin use were associated with an increased risk of having an infant with DIV, while maternal lipid intake had an inverse association. These novel data provide multiple metabolic pathways for investigation to identify better the developmental etiologies of DIV and suggest that public health interventions targeting diabetes prevention and management in women of childbearing age could reduce CHD risk.
Keyphrases
- congenital heart disease
- pregnancy outcomes
- type diabetes
- glycemic control
- public health
- cardiovascular disease
- pregnant women
- birth weight
- polycystic ovary syndrome
- weight gain
- physical activity
- electronic health record
- big data
- pulmonary hypertension
- mitral valve
- preterm birth
- cancer therapy
- fatty acid
- coronary artery
- breast cancer risk
- deep learning
- atrial fibrillation