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Novel spore-forming species exhibiting intrinsic resistance to third- and fourth-generation cephalosporins and description of Tigheibacillus jepli gen. nov., sp. nov.

Georgios MiliotisPratyay SenguptaAsif HameedMaria ChuvochinaFrancesca McDonaghAnna C SimpsonCeth W ParkerNitin K SinghPunchappady-Devasya RekhaDearbháile MorrisKarthik RamanNikos C KyrpidesPhilip HugenholtzKasthuri Venkateswaran
Published in: mBio (2024)
family, aligning genetic identities with phylogenetic data. Investigating ARG and virulence factors (VF) across these strains illuminates the microbial capability for resistance under resource-limited conditions while emphasizing the role of human-associated VF in microbial survival, informing sterilization practices and microbial management in similar oligotrophic settings beyond spacecraft assembly cleanrooms such as pharmaceutical and medical industry cleanrooms.
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