Research of recombinant influenza A virus as a vector for Mycoplasma pneumoniae P1a and P30a.
Liang YuWang YongboYang ShengjunTan JiaXu YaLiao GuoyangMa LinnaPublished in: Immunity, inflammation and disease (2024)
The recombinant viruses rFLU-P1a and rFLU-P30a which carried the advantaged immune regions of the P1 and P30 genes in MP were successfully constructed and identified. And the genetic stability of rFLU-P1a or rFLU-P30a was relatively high. The typical and complete morphology of influenza virus was observed under the electron microscope. Our research provided a foundation for the further development of MP vaccines for human.