Age-Dependent Effects of Voluntary Wheel Running Exercise on Voiding Behavior and Potential Age-Related Molecular Mechanisms in Mice.
Teresa T LiuLaura E PascalScott R BauerHannah N MilesJules B PankseppGranville L LloydLingjun LiDonald B DeFrancoWilliam A RickePublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2024)
Voluntary aerobic exercise improves voiding behavior and mobility, and decreases prostatic mitochondrial protein expression and inflammation in aged mice. This promising model could be used to evaluate molecular mechanisms of aerobic exercise as a novel lifestyle intervention for older men with LUTS/BPH.
Keyphrases
- benign prostatic hyperplasia
- lower urinary tract symptoms
- physical activity
- oxidative stress
- high intensity
- high fat diet induced
- middle aged
- randomized controlled trial
- metabolic syndrome
- cardiovascular disease
- type diabetes
- wild type
- human health
- risk assessment
- radical prostatectomy
- skeletal muscle
- climate change