Evaluating the efficacy of biologics with and without methotrexate in the treatment of psoriatic arthritis: a network meta-analysis.

Phillip J MeaseSoumya ReddySarah RossJeffrey R LissePaulo ReisKirstin GriffingChristophe SapinAisha VadhariyaDaniel E Furst

Published in: RMD open (2024)

Concomitant use of MTX and biologics did not improve ACR efficacy outcomes versus biologic monotherapy. MTX does not appear to be necessary as a background therapy when biologics are used for the achievement of ACR20/50 responses in patients with PsA.

Keyphrases

prostate cancer
combination therapy
rheumatoid arthritis
high dose
randomized controlled trial
open label
type diabetes
stem cells
metabolic syndrome
weight loss
insulin resistance
glycemic control
double blind