Significance of urinary fatty acid-binding protein 4 level as a possible biomarker for the identification of minimal change disease in patents with nephrotic-range proteinuria.

Marenao TanakaMasato FuruhashiNorihito MoniwaTakuto MaedaHideki TakizawaMegumi MatsumotoAkiko SakaiYukimura HigashiuraYufu GochoMasayuki KoyamaYayoi OgawaTetsuji Miura

Published in: BMC nephrology (2020)

U-FABP4 level is independently associated with proteinuria and renal dysfunction in patients with glomerular kidney disease. A low U-FABP4 level may predict MCNS in patients with nephrotic syndrome and would be a useful biomarker for differential diagnosis of MCNS and MN, which are common causes of nephrotic syndrome.

Keyphrases

binding protein
fatty acid
oxidative stress
room temperature
bioinformatics analysis
ionic liquid