Long non-coding RNA H19 expression and functional polymorphism rs217727 are linked to increased ischemic stroke risk.

Mohadese RezaeiMohammad Javad MokhtariMahnaz BayatAnahid SafariMehdi DianatpuorReza TabriziTahereh AsadabadiAfshin Borhani-Haghighi

Published in: BMC neurology (2021)

The rs217727 polymorphism of the H19 is correlated with IS susceptibility, and H19 expression levels were higher in SVO and LAA patients. The upregulation of H19 may be considered as a diagnostic biomarker in IS among the Iranian population, but it cannot serve as a useful prognostic marker.

Keyphrases

poor prognosis
long non coding rna
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
cell proliferation
binding protein
patient reported