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Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data.

Hung MaiJingxuan BaoPaul M ThompsonDokyoon KimLi Shen
Published in: BMC bioinformatics (2022)
These results confirm that S-PrediXcan can identify genes with tissue-specific transcriptomic effects on complex traits. The analysis also suggested novel genes whose expression levels are related to brain volumetric traits. This provides important insights into the genetic mechanisms of the human brain.
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