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Exploring the prognostic potential of m6A methylation regulators in low-grade glioma: implications for tumor microenvironment modulation.

Honggang WuSiqi ChenZiliang HuRong GeLu MaChao YouYi Huang
Published in: European journal of medical research (2024)
Our results present that the m6A regulators play vital role in regulating PD-L1/PD-1 expression and the infiltration of immune cells, thereby exerting a sizable impact on the TIME of LGG. Therefore, m6A regulators have precise predictive value in the prognosis of LGG.
Keyphrases
  • low grade
  • transcription factor
  • high grade
  • poor prognosis
  • dna methylation
  • genome wide
  • binding protein
  • gene expression
  • long non coding rna