Galectin-1 and -3 in high amounts inhibit angiogenic properties of human retinal microvascular endothelial cells in vitro.

Anna HillenmayerChristian M WertheimerArie GeerlofKirsten H EiblSiegfried PriglingerClaudia PriglingerAndreas Ohlmann

Published in: PloS one (2022)

Exogenously added hr-GAL1 or 3 inhibit angiogenic properties of HRMEC in vitro, an effect that might be mediated via a loss of intracellular endogenous galectins.

Keyphrases

endothelial cells
high glucose
optical coherence tomography
diabetic retinopathy
vascular endothelial growth factor
induced pluripotent stem cells
pluripotent stem cells