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A multifaceted gradient in human cerebellum of structural and functional development.

Xingyu LiuFederico d'Oleire UquillasAngela N ViaeneZonglei ZhenJesse Gomez
Published in: Nature neuroscience (2022)
The organization of the basic tissue and functional properties of the cerebellum across development is unknown. Combining several large datasets, we demonstrate in the human cerebellum a static tissue gradient in adults that mirrors a similar growth-rate gradient across development. Quantitative tissue metrics corroborate unique densities of certain lipids and proteins among lobules, and cerebellar structural development closely follows cerebellar functional properties through childhood.
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