Very low calorie diets are associated with transient ventricular impairment before reversal of diastolic dysfunction in obesity.
Jennifer J RaynerInes AbdesselamMark A PeterzanIoannis AkoumianakisNadia AkawiCharalambos AntoniadesJeremy W TomlinsonStefan NeubauerOliver J RiderPublished in: International journal of obesity (2005) (2018)
Whilst VLCDs result in dramatic improvements in insulin resistance, they are associated with transient but significant cardiovascular functional decline, which may have an impact on those with the coexisting cardiac disease. However, after 8 weeks, the diet was associated with normalisation of cardiac function, suggesting they may form a potential therapeutic intervention for diastolic dysfunction in obesity and diabetes.
Keyphrases
- weight loss
- insulin resistance
- left ventricular
- type diabetes
- glycemic control
- high fat diet induced
- metabolic syndrome
- adipose tissue
- blood pressure
- oxidative stress
- high fat diet
- skeletal muscle
- cerebral ischemia
- heart failure
- polycystic ovary syndrome
- randomized controlled trial
- weight gain
- physical activity
- gestational age
- catheter ablation