Investigating the Expression Pattern of the SETMAR Gene Transcript Variants in Childhood Acute Leukemia: Revisiting an Old Gene.

Samaneh Boroumand-NoughabiAli PashaeeMehdi MontazerAtefe RahmatiHossein AyatollahiMohammad Hadi SadeghianMohammad Reza Keramati

Published in: Journal of pediatric hematology/oncology (2023)

According to the results, SETMAR showed increased expression in pediatric acute leukemia's bone marrow samples, indicating a role for this molecule in leukemia pathogenesis. As this is the first report of SETMAR expression in pediatric leukemias, further studies are needed to investigate the causality of this association.

Keyphrases

poor prognosis
bone marrow
copy number
binding protein
genome wide
mesenchymal stem cells
emergency department
acute myeloid leukemia
long non coding rna
dna methylation
young adults
rna seq