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Cefepime-induced neurotoxicity: systematic review.

Gozun MaanKoichi KeitokuNobuhiko KimuraHaruki SawadaAndrew PhamJihun YeoHideharu HagiyaYoshito Nishimura
Published in: The Journal of antimicrobial chemotherapy (2022)
This systematic review summarizes the current evidence and characteristics of CIN. In the current situation where there are no CIN diagnostic criteria and the drug monitoring platform is not routinely available, candidates for cefepime should be carefully selected. Also, based on these findings, it needs to be appropriately dosed to avoid the development of CIN.
Keyphrases
  • systematic review
  • meta analyses
  • randomized controlled trial
  • high throughput
  • high glucose
  • diabetic rats
  • oxidative stress