Nine-gene pharmacogenomics profile service: The Mayo Clinic experience.

Eric T MateyAshley Kate RaganLance J OyenCarolyn R Rohrer VitekStacy L AoudiaAhmed K RagabKelliann C Fee-SchroederJohn L BlackAnn M MoyerWayne T NicholsonSofia ShresthaTammy M McAllisterJason P SinnwellStephanie S FaubionKonstantinos N Lazaridis

Published in: The pharmacogenomics journal (2021)

The Mayo Clinic PGx (PGx) Profile Service was a proof-of-concept project to utilize PGx testing as another clinical tool to enhance medication selection and decrease serious adverse reactions or medication failures. Over one-half of participants in the pilot using the PGx Profile Service were predicted to benefit from pre-emptive PGx testing to guide pharmacotherapy. PGx pharmacists played a crucial role in the PGx Profile Service by educating participants, identifying medication-gene interactions, and providing evidence-based (CPIC and DPWG) PGx recommendations for past, current, and future medication us.

Keyphrases

healthcare
mental health
adverse drug
primary care
genome wide
copy number
emergency department
randomized controlled trial
gene expression
quality improvement
study protocol
smoking cessation