Andrographolide protects against doxorubicin-and arsenic trioxide-induced toxicity in cardiomyocytes.
Leila SafaeianFatemeh ShafieeSamira HaghighatnazarPublished in: Molecular biology reports (2022)
In conclusion, these data presented that AG was able to reverse DOX- and ATO-induced cardiotoxicity in vitro. The cardiomyocyte protective activities of AG may be due to the decrease in TLR4 expression and total oxidant capacity and increase in total antioxidant capacity.
Keyphrases
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