Improved preoperative risk stratification with CA-125 in low-grade endometrial cancer: a multicenter prospective cohort study.
Casper ReijnenNicole C M VisserJenneke C KasiusDorry BollPeggy Maj GeominiHuy NgoDennis Van HamontBrenda M PijlmanMaria Caroline VosJohan BultenMarc P M L SnijdersLeon F A G MassugerJohanna M A PijnenborgPublished in: Journal of gynecologic oncology (2020)
Preoperative elevated CA-125 was associated with poor prognostic features and independently associated with DFS and DSS. Particularly patients with low-grade EC and elevated CA-125 represent a group with poor outcome and should be considered as high-risk endometrial carcinoma.