HSPA4 upregulation induces immune evasion via ALKBH5/CD58 axis in gastric cancer.

Daqin SuoXiaoling GaoQingyun ChenTingting ZengJiarong ZhanGuanghui LiYinli ZhengSenlin ZhuJingping YunXin-Yuan GuanYan Li

Published in: Journal of experimental & clinical cancer research : CR (2024)

T cell's cytotoxicity, finally induces immune evasion of GC cells. HSPA4 upregulation is associated with worse overall survival of GC patients with only surgery. Meanwhile, HSPA4 upregulation predicts for better response in GC patients receiving the combined immunotherapy.

Keyphrases

poor prognosis
heat shock protein
cell proliferation
signaling pathway
induced apoptosis
gas chromatography
minimally invasive
coronary artery bypass
long non coding rna
endoplasmic reticulum stress
coronary artery disease
surgical site infection
acute coronary syndrome