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Detection of PSMA expression on circulating tumor cells by blood-based liquid biopsy in prostate cancer.

Santosh GuptaLuisa FernandezDavid BourdonAnis A HamidAnupama PasamErnest LamRichard WenstrupShahneen Sandhu
Published in: Journal of circulating biomarkers (2024)
The analytical validation utilizing Epic Sciences' liquid biopsy CTC platform demonstrated the potential to detect PSMA protein expression in CTCs from patients with mCRPC. This assay is positioned as an effective research tool to evaluate PSMA expression, heterogeneity, and therapeutic response in many ongoing clinical studies to target tumors that express PSMA.
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