Utility of the dual antiplatelet therapy score to guide antiplatelet therapy: A systematic review and meta-analysis.

Nino MihatovEric A SecemskyDean J KereiakesGabriel StegPatrick W J C SerruysPly ChichareonChangyu ShenRobert W Yeh

Published in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2020)

In this large meta-analysis, the DAPT score consistently stratified bleeding and ischemic risk in opposing directions across several different study populations. More evaluation is needed to understand if the effect of longer DAPT duration on NACE is modified by the DAPT score in current practice.

Keyphrases

antiplatelet therapy
acute coronary syndrome
percutaneous coronary intervention
systematic review
primary care
coronary artery disease
randomized controlled trial
oxidative stress
quality improvement
blood brain barrier
cerebral ischemia