Login / Signup

Pediatric Antibiotic Stewardship for Community-Acquired Pneumonia: A Pre-Post Intervention Study.

Herman Avner CohenMaya GersteinYiska Loewenberg WeisbandYael RichenbergEyal JacobsonMoriya CohenVered Shkalim ZemerMaayan Diti Machnes
Published in: Clinical pediatrics (2022)
We aimed to investigate the effectiveness of an antibiotic stewardship program (ASP) on antibiotic prescription in children with community-acquired pneumonia (CAP). Antibiotic purchasing data were collected for children aged 3 months to 18 years diagnosed with CAP from November 2016 to April 2017 (pre-intervention period) and from November 2017 to April 2018 (post-intervention period). The intervention was a 1-day seminar for primary care pediatricians on the diagnosis and treatment of CAP in children according to national guidelines. There was a substantial decrease in the use of azithromycin after the intervention. In younger children, there was a 42% decrease, alongside an increased use of amoxicillin (<i>P</i> &lt; .001). In older children, there was a smaller, non-statistically significant decrease in the use of azithromycin (<i>P</i> = .45). Our data demonstrate that the implementation of an ASP was associated with a reduction in the use of broad-spectrum antibiotics and macrolides and increased guideline adherence for the safe treatment of CAP.
Keyphrases
  • randomized controlled trial
  • community acquired pneumonia
  • primary care
  • young adults
  • quality improvement
  • systematic review
  • healthcare
  • physical activity
  • machine learning
  • adipose tissue
  • data analysis
  • acute care