The association between adverse childhood experiences and alterations in brain volume and cortical thickness in adults with alcohol use disorder.
Cagdas TürkmenHaoye TanSarah GerhardtEmilie BougeletMaria BernardoNoah MachunzeYasmin GrauduszusMaurizio SicorelloTraute DemirakcaFalk KieferSabine Vollstädt-KleinPublished in: Addiction biology (2024)
In adults with AUD, abuse experienced during early adolescence is associated with reduced CT in regions involved in inhibitory control, indicating the potential relevance of cognitive pathways in the association between ACE and AUD. Longitudinal studies are needed to confirm and expand upon current findings.
Keyphrases
- alcohol use disorder
- image quality
- depressive symptoms
- computed tomography
- resting state
- dual energy
- white matter
- optical coherence tomography
- mental health
- contrast enhanced
- angiotensin ii
- angiotensin converting enzyme
- case control
- cross sectional
- functional connectivity
- early life
- positron emission tomography
- cerebral ischemia
- human health
- magnetic resonance imaging
- adverse drug
- intimate partner violence
- blood brain barrier