Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat.

Luisa Alessandra Atehortua-MartinezCyriaque MasnierePatrizia CampolongoStéphanie ChasseigneauxJacques CallebertClemens ZwergelAntonello MaiJean-Louis LaplancheHuixiong ChenMélanie Etheve-QuelquejeuBruno MégarbaneNadia Benturquia

Published in: Journal of psychopharmacology (Oxford, England) (2019)

Our findings clearly show that MDPV produces profound behavioral alterations mediated by the activation of the dopaminergic system similarly to other amphetamines.

Keyphrases

drug induced
liver failure
respiratory failure
intellectual disability
oxidative stress
aortic dissection
adverse drug
hepatitis b virus
intensive care unit
mechanical ventilation