Clemens Zwergel

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 33

Top Topics

Idiopathic Pulmonary Fibrosis

Histone Deacetylase

Cognitive Decline

Top Venues

Journal of medicinal chemistry

Cell death discovery

Expert opinion on therapeutic patents

This page only lists publications with an associated author ORCID identifier.

Publications

Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry 67 (3) (2024)
Clemens Zwergel, Rossella Fioravanti, Giulia Stazi, Federica Sarno, Cecilia Battistelli, Annalisa Romanelli, Angela Nebbioso, Eduarda Mendes, Alexandra Paulo, Raffaele Strippoli, Marco Tripodi, Dany Pechalrieu, Paola Barbara Arimondo, Teresa De Luca, Donatella Del Bufalo, Daniela Trisciuoglio, Lucia Altucci, Sergio Valente, Antonello Mai
Correction: Zwergel et al. Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation. Cancers 2020, 12 , 447. Cancers 16 (6) (2024)
Clemens Zwergel, Rossella Fioravanti, Giulia Stazi, Federica Sarno, Cecilia Battistelli, Annalisa Romanelli, Angela Nebbioso, Eduarda Mendes, Alexandra Paulo, Raffaele Strippoli, Marco Tripodi, Dany Pechalrieu, Paola Barbara Arimondo, Teresa De Luca, Donatella Del Bufalo, Daniela Trisciuoglio, Lucia Altucci, Sergio Valente, Antonello Mai
Correction: Zwergel et al. Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation. Cancers 2020, 12 , 447. Cancers 16 (6) (2024)
Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry 67 (3) (2024)
Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry (2024)
Patryk Pyka, Wawrzyniec Haberek, Małgorzata Więcek, Ewa Szymanska, Wesam Ali, Agnieszka Cios, Magdalena Jastrzębska-Więsek, Grzegorz Satała, Sabina Podlewska, Silvia Di Giacomo, Antonella Di Sotto, Sabrina Garbo, Tadeusz Karcz, Chiara Lambona, Francesco Marocco, Gniewomir Latacz, Sylwia Sudoł-Tałaj, Barbara Mordyl, Monika Głuch-Lutwin, Agata Siwek, Kinga Czarnota-Łydka, Dawid Gogola, Agnieszka Olejarz-Maciej, Natalia Wilczyńska-Zawal, Ewelina Honkisz-Orzechowska, Małgorzata Starek, Monika Dąbrowska, Katarzyna Kucwaj-Brysz, Rossella Fioravanti, Muhammad Jawad Nasim, Marius Hittinger, Anna Partyka, Anna Wesołowska, Cecilia Battistelli, Clemens Zwergel, Jadwiga Handzlik
First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT 6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease. Journal of medicinal chemistry (2024)
Patryk Pyka, Wawrzyniec Haberek, Małgorzata Więcek, Ewa Szymanska, Wesam Ali, Agnieszka Cios, Magdalena Jastrzębska-Więsek, Grzegorz Satała, Sabina Podlewska, Silvia Di Giacomo, Antonella Di Sotto, Sabrina Garbo, Tadeusz Karcz, Chiara Lambona, Francesco Marocco, Gniewomir Latacz, Sylwia Sudoł-Tałaj, Barbara Mordyl, Monika Głuch-Lutwin, Agata Siwek, Kinga Czarnota-Łydka, Dawid Gogola, Agnieszka Olejarz-Maciej, Natalia Wilczyńska-Zawal, Ewelina Honkisz-Orzechowska, Małgorzata Starek, Monika Dąbrowska, Katarzyna Kucwaj-Brysz, Rossella Fioravanti, Muhammad Jawad Nasim, Marius Hittinger, Anna Partyka, Anna Wesołowska, Cecilia Battistelli, Clemens Zwergel, Jadwiga Handzlik
First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT 6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease. Journal of medicinal chemistry 67 (2) (2024)
Matteo Cassandri, Antonella Porrazzo, Silvia Pomella, Beatrice Noce, Clemens Zwergel, Francesca Antonella Aiello, Francesca Vulcano, Luisa Milazzo, Simona Camero, Deborah Pajalunga, Massimo Spada, Valeria Manzi, Giovanni Luca Gravina, Silvia Codenotti, Michela Piccione, Miriam Tomaciello, Michele Signore, Giovanni Barillari, Cinzia Marchese, Alessandro Fanzani, Biagio De Angelis, Concetta Quintarelli, Christopher R Vakoc, Eleanor Y Chen, Francesca Megiorni, Franco Locatelli, Sergio Valente, Antonello Mai, Rossella Rota, Francesco Marampon
HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks. Cell death discovery 10 (1) (2024)
Patryk Pyka, Wawrzyniec Haberek, Małgorzata Więcek, Ewa Szymanska, Wesam Ali, Agnieszka Cios, Magdalena Jastrzębska-Więsek, Grzegorz Satała, Sabina Podlewska, Silvia Di Giacomo, Antonella Di Sotto, Sabrina Garbo, Tadeusz Karcz, Chiara Lambona, Francesco Marocco, Gniewomir Latacz, Sylwia Sudoł-Tałaj, Barbara Mordyl, Monika Głuch-Lutwin, Agata Siwek, Kinga Czarnota-Łydka, Dawid Gogola, Agnieszka Olejarz-Maciej, Natalia Wilczyńska-Zawal, Ewelina Honkisz-Orzechowska, Małgorzata Starek, Monika Dąbrowska, Katarzyna Kucwaj-Brysz, Rossella Fioravanti, Muhammad Jawad Nasim, Marius Hittinger, Anna Partyka, Anna Wesołowska, Cecilia Battistelli, Clemens Zwergel, Jadwiga Handzlik
First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT 6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease. Journal of medicinal chemistry 67 (2) (2024)
Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry 67 (3) (2024)
Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry 67 (3) (2024)
Alessia Raucci, Carola Castiello, Antonello Mai, Clemens Zwergel, Sergio Valente
Heterocycles-Containing HDAC Inhibitors Active in Cancer: An Overview of the Last Fifteen Years. ChemMedChem (2024)
Matteo Cassandri, Antonella Porrazzo, Silvia Pomella, Beatrice Noce, Clemens Zwergel, Francesca Antonella Aiello, Francesca Vulcano, Luisa Milazzo, Simona Camero, Deborah Pajalunga, Massimo Spada, Valeria Manzi, Giovanni Luca Gravina, Silvia Codenotti, Michela Piccione, Miriam Tomaciello, Michele Signore, Giovanni Barillari, Cinzia Marchese, Alessandro Fanzani, Biagio De Angelis, Concetta Quintarelli, Christopher R Vakoc, Eleanor Y Chen, Francesca Megiorni, Franco Locatelli, Sergio Valente, Antonello Mai, Rossella Rota, Francesco Marampon
HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks. Cell death discovery 10 (1) (2024)
Chiara Lambona, Clemens Zwergel, Sergio Valente, Antonello Mai
SIRT3 Activation a Promise in Drug Development? New Insights into SIRT3 Biology and Its Implications on the Drug Discovery Process. Journal of medicinal chemistry 67 (3) (2024)
Matteo Cassandri, Antonella Porrazzo, Silvia Pomella, Beatrice Noce, Clemens Zwergel, Francesca Antonella Aiello, Francesca Vulcano, Luisa Milazzo, Simona Camero, Deborah Pajalunga, Massimo Spada, Valeria Manzi, Giovanni Luca Gravina, Silvia Codenotti, Michela Piccione, Miriam Tomaciello, Michele Signore, Giovanni Barillari, Cinzia Marchese, Alessandro Fanzani, Biagio De Angelis, Concetta Quintarelli, Christopher R Vakoc, Eleanor Y Chen, Francesca Megiorni, Franco Locatelli, Sergio Valente, Antonello Mai, Rossella Rota, Francesco Marampon
HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks. Cell death discovery 10 (1) (2024)
Patryk Pyka, Wawrzyniec Haberek, Małgorzata Więcek, Ewa Szymanska, Wesam Ali, Agnieszka Cios, Magdalena Jastrzębska-Więsek, Grzegorz Satała, Sabina Podlewska, Silvia Di Giacomo, Antonella Di Sotto, Sabrina Garbo, Tadeusz Karcz, Chiara Lambona, Francesco Marocco, Gniewomir Latacz, Sylwia Sudoł-Tałaj, Barbara Mordyl, Monika Głuch-Lutwin, Agata Siwek, Kinga Czarnota-Łydka, Dawid Gogola, Agnieszka Olejarz-Maciej, Natalia Wilczyńska-Zawal, Ewelina Honkisz-Orzechowska, Małgorzata Starek, Monika Dąbrowska, Katarzyna Kucwaj-Brysz, Rossella Fioravanti, Muhammad Jawad Nasim, Marius Hittinger, Anna Partyka, Anna Wesołowska, Cecilia Battistelli, Clemens Zwergel, Jadwiga Handzlik
First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT 6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease. Journal of medicinal chemistry 67 (2) (2024)
Clemens Zwergel, Michele Aventaggiato, Sabrina Garbo, Elisabetta Di Bello, Bruno Fassari, Beatrice Noce, Carola Castiello, Chiara Lambona, Federica Barreca, Dante Rotili, Rossella Fioravanti, Thomas Schmalz, Michael Weyand, Amelie Niedermeier, Marco Tripodi, Gianni Colotti, Clemens Steegborn, Cecilia Battistelli, Marco Tafani, Sergio Valente, Antonello Mai
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells. Journal of medicinal chemistry (2023)
Sabrina Garbo, Silvia Di Giacomo, Dorota Łażewska, Ewelina Honkisz-Orzechowska, Antonella Di Sotto, Rossella Fioravanti, Clemens Zwergel, Cecilia Battistelli
Selenium-Containing Agents Acting on Cancer-A New Hope? Pharmaceutics 15 (1) (2022)
Sabrina Garbo, Silvia Di Giacomo, Dorota Łażewska, Ewelina Honkisz-Orzechowska, Antonella Di Sotto, Rossella Fioravanti, Clemens Zwergel, Cecilia Battistelli
Selenium-Containing Agents Acting on Cancer-A New Hope? Pharmaceutics 15 (1) (2022)
Jacopo Morroni, Leonardo Schirone, Valentina Valenti, Clemens Zwergel, Carles Sánchez Riera, Sergio Valente, Daniele Vecchio, Sonia Schiavon, Rino Ragno, Antonello Mai, Sebastiano Sciarretta, Biliana Lozanoska-Ochser, Marina Bouché
Inhibition of PKCθ Improves Dystrophic Heart Phenotype and Function in a Novel Model of DMD Cardiomyopathy. International journal of molecular sciences 23 (4) (2022)
Rossella Fioravanti, Veronica Rodriguez, Jonatan Caroli, Ugo Chianese, Rosaria Benedetti, Elisabetta Di Bello, Beatrice Noce, Clemens Zwergel, Davide Corinti, Dolores Viña, Lucia Altucci, Andrea Mattevi, Sergio Valente, Antonello Mai
Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Benjamin Suenkel, Sergio Valente, Clemens Zwergel, Sandra Weiss, Elisabetta Di Bello, Rossella Fioravanti, Michele Aventaggiato, João A Amorim, Neha Garg, Surinder Kumar, David B Lombard, Tuo Hu, Pankaj K Singh, Marco Tafani, Carlos M Palmeira, David Sinclair, Antonello Mai, Clemens Steegborn
Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5. Journal of medicinal chemistry 65 (20) (2022)
Sabrina Garbo, Silvia Di Giacomo, Dorota Łażewska, Ewelina Honkisz-Orzechowska, Antonella Di Sotto, Rossella Fioravanti, Clemens Zwergel, Cecilia Battistelli
Selenium-Containing Agents Acting on Cancer-A New Hope? Pharmaceutics 15 (1) (2022)
Elisabetta Di Bello, Beatrice Noce, Rossella Fioravanti, Clemens Zwergel, Sergio Valente, Dante Rotili, Giulia Fianco, Daniela Trisciuoglio, Marina M Mourão, Policarpo Sales, Suzanne Lamotte, Eric Prina, Gerald F Späth, Cécile Häberli, Jennifer Keiser, Antonello Mai
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi , Leishmania , and Schistosoma mansoni . ACS infectious diseases 8 (7) (2022)
Giulio Bontempi, Michela Terri, Sabrina Garbo, Claudia Montaldo, Davide Mariotti, Veronica Bordoni, Sergio Valente, Clemens Zwergel, Antonello Mai, Alessandra Marchetti, Alessandro Domenici, Paolo Menè, Cecilia Battistelli, Marco Tripodi, Raffaele Strippoli
Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells. Cell death & disease 13 (11) (2022)
Daohai Du, Dandan Xu, Licheng Zhu, Giulia Stazi, Clemens Zwergel, Yanli Liu, Zhongyuan Luo, Yuanqing Li, Yuanyuan Zhang, Kongkai Zhu, Yiluan Ding, Jingqiu Liu, Shijie Fan, Kaiyan Zhao, Naixia Zhang, Xiangqian Kong, Hualiang Jiang, Kaixian Chen, Kehao Zhao, Sergio Valente, Jinrong Min, Wenhu Duan, Cheng Luo
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction. Journal of medicinal chemistry 64 (12) (2021)
Stefano Tomassi, Annalisa Romanelli, Clemens Zwergel, Sergio Valente, Antonello Mai
Polycomb Repressive Complex 2 Modulation through the Development of EZH2-EED Interaction Inhibitors and EED Binders. Journal of medicinal chemistry 64 (16) (2021)
Nicola Mautone, Clemens Zwergel, Antonello Mai, Dante Rotili
Sirtuin modulators: where are we now? A review of patents from 2015 to 2019. Expert opinion on therapeutic patents 30 (6) (2020)
Silvia Caroselli, Clemens Zwergel, Adele Pirolli, Manuela Sabatino, Zhanjie Xu, Gilbert Kirsch, Antonello Mai, Gianni Colotti, Fabio Altieri, Rita Canipari, Sergio Valente, Rino Ragno
Discovery of the First Human Arylsulfatase A Reversible Inhibitor Impairing Mouse Oocyte Fertilization. ACS chemical biology 15 (6) (2020)
Sara Schiavi, Francesca Melancia, Emilia Carbone, Valeria Buzzelli, Antonia Manduca, Patricia Jiménez Peinado, Clemens Zwergel, Antonello Mai, Patrizia Campolongo, Louk J M J Vanderschuren, Viviana Trezza
Detrimental effects of the 'bath salt' methylenedioxypyrovalerone on social play behavior in male rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 45 (12) (2020)
Luisa Alessandra Atehortua-Martinez, Cyriaque Masniere, Patrizia Campolongo, Stéphanie Chasseigneaux, Jacques Callebert, Clemens Zwergel, Antonello Mai, Jean-Louis Laplanche, Huixiong Chen, Mélanie Etheve-Quelquejeu, Bruno Mégarbane, Nadia Benturquia
Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat. Journal of psychopharmacology (Oxford, England) 33 (3) (2019)
Maria Cristina Manara, Sergio Valente, Camilla Cristalli, Giordano Nicoletti, Lorena Landuzzi, Clemens Zwergel, Roberta Mazzone, Giulia Stazi, Paola B Arimondo, Michela Pasello, Clara Guerzoni, Piero Picci, Patrizia Nanni, Pier-Luigi Lollini, Antonello Mai, Katia Scotlandi
A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy. Molecular cancer therapeutics 17 (9) (2018)
Giulia Stazi, Clemens Zwergel, Antonello Mai, Sergio Valente
EZH2 inhibitors: a patent review (2014-2016). Expert opinion on therapeutic patents 27 (7) (2017)