Development of type 2 diabetes in adolescent girls with polycystic ovary syndrome and obesity.

Julia Hudnut-BeumlerJill Landsbaugh KaarAnya TaylorMegan M Kelsey Kristen J Nadeau Philip S Zeitler Janet K Snell-Bergeon Laura L Pyle Melanie Cree Green

Published in: Pediatric diabetes (2021)

Girls with PCOS and obesity have an 18-fold increase in T2D incidence compared to published rates in non-PCOS youth. Hispanic girls with elevated HbA1c and ALT are at particular risk. Due to the morbidity associated with youth onset T2D, these findings argue for better screening and prevention approaches in this population.

Keyphrases

type diabetes
insulin resistance
polycystic ovary syndrome
metabolic syndrome
weight loss
high fat diet induced
mental health
physical activity
young adults
weight gain
adipose tissue
glycemic control
risk factors
skeletal muscle
body mass index
african american
randomized controlled trial